Saturday, October 31, 2020
Friday, October 30, 2020
Wednesday, October 28, 2020
9th Grade. Nucleic Acids
DNA & RNA (Nucleic Acids)
If the primary structure of polypeptides determines a protein’s shape, what determines primary structure? The amino acid sequence of a polypeptide is programmed by a discrete unit of inheritance known as a gene. Genes consist of DNA, which belongs to the class of compounds called nucleic acids. Nucleic acids are polymers made of monomers called nucleotides.The two types of nucleic acids, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), enable living organisms to reproduce their complex components from one generation to the next. Unique among molecules, DNA provides directions for its own replication. DNA also directs RNA synthesis and, through RNA, controls protein synthesis; this entire process is called gene expression.A gene’s meaning to the cell is encoded in its specific sequence of the four DNA bases. DNA molecules have two polynucleotides, or “strands,” that wind around an imaginary axis, forming a double helix. In base pairing, only certain bases in the double helix are compatible with each other. Adenine (A) in one strand always pairs with thymine (T) in the other, and guanine (G) always pairs with cytosine (C). Note that in RNA, adenine (A) pairs with uracil (U); thymine (T) is not present in RNA.
- How can a DNA act as a blueprint for something as complex and wonderful as a dog?
- Explain the chain of events from DNA molecule to the protein.
8th Grade small Online quiz
Hey everyone. This is the last opportunity to grab some grade.
Title: Bones and Muscles Quiz
Purpose: to enjoy and get more knowledge and practical skills
Quiz: LINK is here
Tuesday, October 27, 2020
The newest lesson. 10th grade
Monday, October 26, 2020
The Human Muscles. 8th Grade lesson
- sodium (Na+) 2. calcium (Ca++) 3. potassium (K+)
- What are functions of skeletal muscles?
- What are differences between cardiac and smooth muscles organisation?
9th Grade. Nucleic Acids
Hey everyone. Small story on DNA first. Then video test. Enjoy!
Life’s Enigma Code
In the mid-to-late 1940s, scientists began to suspect that the molecules that are responsible for heredity were not proteins, but in fact DNA, short for deoxyribonucleic acid. But how could a molecule long considered to be simple and inert hold the secret of life? The Nobel Prize in Physiology or Medicine in 1962 was awarded to James Watson, Francis Crick and Maurice Wilkins for their discovery of the molecular structure of DNA, which helped solve one of the most important of all biological riddles.
Wilkins and his colleague Rosalind Franklin provided the key X-ray diffraction patterns that Watson and Crick used, as well as information from many other scientists, to build the definitive model of DNA’s structure. The structure, as simple and elegant as it is profound, shows that two long strands of DNA run in opposite directions and spiral around one another in the shape of a double helix. Another vital element in the structure is that four organic bases – known as adenine, thymine, cytosine and guanine – are paired in a specific manner between the two helices in such a way as to provide a natural scaffold for the two strands.
Watson and Crick’s structure of DNA could also explain how information is transferred in living material. The specific base pairing facilitates the perfect copying facility for heredity, while the specific order of bases forms the blueprint for the sequence of amino acids in a protein. DNA molecules can ‘unzip’ into two separate strands, and when the cell’s machinery creates matching strands, the specific pairing between the bases ensures that you get two faithful copies where you had one before. Watson and Crick’s paper revealing the structure, published in Nature on 25 April 1953, contains perhaps one of scientific literature’s most famous understatements: “It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.”
Thursday, October 22, 2020
9th Grade. Organic molecules lesson. Proteins
Proteins
Vocabulary
enzymes
carrier
side chain
polypeptide
to denaturate
1 (pair work). Which of these things are proteins? Can you think of other examples?
1 egg-white 2 hemoglobin 3 green leaf
2 (individual work). True or False. Correct the false sentences. Use the text below.
1___Proteins are made of nucleic acids.
2___Function of the protein changes with the shape.
3___Amino acids differ from each other in the amino groups.
4___All amino acids have carboxyl group and amino group.
5___Usually enzymes are proteins.
3 (individual work). Answer questions.
A. What is an amino acid?
B. What are differences between four levels of proteins?
Proteins are a class of macromolecules that perform a diverse range of functions for the cell. They help in metabolism by providing structural support and by acting as enzymes, carriers, or hormones. The building blocks of proteins (monomers) are amino acids. Each amino acid has a central carbon that is linked to an amino group, a carboxyl group, a hydrogen atom, and an R group or side chain. There are 20 commonly occurring amino acids, each of which differs in the R group. Each amino acid is linked to its neighbours by a peptide bond. A long chain of amino acids is known as a polypeptide.Proteins are organised at four levels: primary, secondary, tertiary, and quaternary. The primary structure is the unique sequence of amino acids. The local folding of the polypeptide to form structures such as the α helix and β-pleated sheet makes the secondary structure. The overall three dimensional structure is the tertiary structure. When two or more polypeptides combine to form the complete protein structure, the configuration is known as the quaternary structure of a protein. Protein shape and function are linked; any change in shape caused by changes in temperature or pH may lead to protein denaturation and a loss in function.
6 (team work). Discuss answers with your team.
- Why would large proteins be harder to untangle and refold than smaller ones?
- Explain why raw egg white is liquid while boiled egg white is solid and bouncy?
Tuesday, October 20, 2020
Monday, October 19, 2020
Classroom Lab Work. 8th Grade. Bones, Joints, Muscles
Carefully break the largest bone. Do not crush the bone. Observe the red jelly-like tissue inside the bone. Remember this is the bone marrow. Marrow produces all blood cells and platelets for use throughout our body. Red blood cells carry food and oxygen to all cells in our body. Platelets allow blood to clot rather than continue free flowing. Poke the marrow with the point of the scissors to show the consistency of the marrow.
Thursday, October 15, 2020
9th Grade Laboratory Work. Catalase Enzyme Activity
- Enzyme amount
- Substrate (the substance on which an enzyme acts) amount
- Substrate acidity (using vinegar)
- Reaction temperature
Tuesday, October 13, 2020
10th Grade. Science Lesson. Next in a row
8th Grade BYOD. Skeletal System
The 206 bones that compose the adult skeleton are divided into five categories based on their shapes. A long bone is one that is cylindrical in shape, being longer than it is wide. The term describesthe shape of a bone, not its size. Long bones are found in the arms (humerus (upper arm bone), ulna (arm bone), radius) and legs (femur (thigh bone), tibia (lower-leg bone), fibula (leg bone), as well as in the fingers (hand bones, phalanges) and toes (foot bone, phalanges). Long bones function as levers; they move when muscles contract.A short bone is one that is cube-like in shape, being about equal in length, width, and thickness. The only short bones in the human skeleton are in the bones of the wrists and the bones of the tarsus. Short bones provide stability and support as well as some limited motion.A flat bone is typically thin, it is also often curved. Examples include the cranial (skull) bones, the scapulae (shoulder blades), the sternum (breastbone), and the ribs. Flat bones serve as points of joining for muscles and often protect internal organs.An irregular bone does not fit any other classification. These bones have more complex shapes, like the vertebrae that support the spinal cord and protect it from compressive forces. Many facial bones, especially the ones containing channels which contain blood, are classified as irregular bones.A sesamoid bone is a small, round bone that, as the name suggests, is shaped like a sesame seed. These bones form in tendons (the sheaths of tissue that connect bones to muscles) where a great deal of pressure is generated in a joint. The sesamoid bones protect tendons by helping them overcome compressive forces. Sesamoid bones vary in number and placement from person to person but are typically found in tendons associated with the feet, hands, and knees. The patellae (singular = patella) are the only sesamoid bones found in common with every person.
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Monday, October 12, 2020
BYOD 9th Grade. Organic Molecules. Lipids
1 Team work. Answer question “Why is the river otter remains dry after swimming?”
Lipids are the one class of large biological molecules that does not include true polymers, and they are generally not big enough to be considered macromolecules. The compounds called lipids are grouped with each other because they share one important trait: they mix poorly, if at all, with water. The hydrophobic behaviour of lipids is based on their molecular structure. We will focus on the types of lipids that are most biologically important: fats, phospholipids, and steroids.Fats are large molecules assembled from smaller molecules by dehydration reactions. A fat is constructed from two kinds of smaller molecules: glycerol and fatty acids. The relatively nonpolar C-H bonds in the hydrocarbon chains of fatty acids are the reason fats are hydrophobic. In making a fat, three fatty acid molecules are each joined to glycerol by an ester linkage. Phospholipids are essential for cells because they are major constituents of cell membranes. Their structure provides a classic example of how form fits function at the molecular level. Phospholipid is similar to a fat molecule but has only two fatty acids attached to glycerol rather than three. At the surface of a cell, phospholipids are arranged in a similar bilayer. Steroids are lipids characterised by a carbon skeleton consisting of four fused rings. Cholesterol, a type of steroid, is an important molecule in animals. It is a common component of animal cell membranes and is also the compound from which other steroids, such as the vertebrate sex hormones, are made.
- Compare the structure of a fat with that of a phospholipid.
- Why are human sex hormones considered lipids?
- Suppose a membrane surrounded an oil droplet, as it does in the cells of plant seeds and in some animal cells. Draw it.
- What are components of Triglycerides?
- Rank the three types of fat in order from most to least healthy
- Partial hydrogenation of cis (healthy) fats results in trans fats. What do you think full hydrogenation of unsaturated fats results in?
Thursday, October 8, 2020
9th Grade BYOD. Organic Molecules. Carbohydrates
Organic Molecules. Carbohydrates
The macromolecules in three of the four classes of life’s organic compounds—carbohydrates, proteins, and nucleic acids, all except lipids—are chain-like molecules called polymers. A polymer is a long molecule consisting of many similar or identical building blocks linked by covalent bonds, much as a train consists of a chain of cars. The repeating units that serve as the building blocks of a polymer are smaller molecules called monomers. Some monomers also have other functions of their own.
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| Dehydration (making of the molecule) and Hydrolysis (breaking down) reactions |
How many molecules of water are needed to completely hydrolyse a polymer that is ten monomers long?
disaccharides
storage
polysaccharides
monosaccharides
1. Write the formula for a monosaccharide that has three carbons.
2. A dehydration reaction joins two glucose molecules to form maltose. The formula for glucose is C6H12O6. What is the formula for maltose?
1. QUESTION: Why do foods like meat, cheese, and eggs have the lowest glycemic index?
10th Grade Extra CW and materials
Hey everyone. Are you familiar with..
There are two last northern white rhinoceroses known to live in the world. Both are females and both are not capable of having a calf. Doomed to go extinct, right? Not yet. Experts have been developing unique techniques of artificial reproduction that give the northern white rhino and potentially even other rare species a hope to survive.
The northern white rhino (NWR) is perhaps the rarest mammal at the moment. These magnificent creatures roamed freely in large parts of central Africa for hundreds of thousand years. But, due to demand for rhino horn, they were poached to extinction in the wild. Their presence in nature has not been seen since 2007.
There are only two specimens known to humans at present Najin and Fatu. Both females were born in Dvůr Králové Zoo, Czech Republic, in 1989 and 2000, respectively. Thanks to a breeding program that started in the 1970s, Dvůr Králové Zoo is the only animal park in the world where the northern white rhino has been bred. However, it was back in 2000 when the last calf was born. So experts turned to artificial techniques of reproduction. In the zoo, they tried inserting a hormonal implant and artificially inseminated NWR females. But no pregnancy from these techniques occurred.
So, in the hope that natural surroundings close to their original habitat may prompt their breeding, both Najin and Fatu were transported from Dvůr Králové Zoo to Ol Pejeta Conservancy in Kenya in 2009. Ol Pejeta was chosen by experts as the best place to try to save the NWR by getting the last fertile animals from captivity together with the last animals from the wild. Unfortunately, the specimens from the wild have never arrived to Ol Pejeta. The response of the politicians and local leaders of DR Congo was so limp, that the NWR was poached to extinction in DR Congo before they were translocated.
Currently, the only hope for the NWR lies in artificial techniques of reproduction. Apart from in vitro fertilization and embryo transfer, different forms of genetic engineering like a generation of stem cells that could be later used for generating reproductive cells are being explored. These techniques are known, but most of them have not been performed in rhinos. For this reason, an international consortium called BioRescue was founded to develop suitable technologies and working protocols to rescue the NWR and to provide the opportunity to establish a self-sustaining, genetically healthy NWR population which can be reintroduced to the wild.
With the last two females, the situation of the northern white rhino is obviously critical. Unfortunately, the same applies to most of rhinos in the world. Those living in Indonesia, the Javan and the Sumatran rhino, are on the brink of extinction with estimated population of around 70 individuals in each species. It seems that similar techniques of reproduction that are used for saving the northern white rhino may assist with breeding of the Sumatran rhino too.
The largest population of rhinos can be found in Southern Africa with the southern white rhino being the most numerous. Coincidentally, our currently most common rhino was nearly extinct in the early 20th century when there were reportedly less than 20 specimens left. Today their population figure reaches approximately 18 thousand individuals. It indicates that the white rhino may be resilient to so-called genetic bottleneck – a situation in which the size of population of a species is significantly reduced. And as the southern white rhino made it through its bottleneck a hundred years ago, it nourishes hopes that the northern white rhino could make it through its bottleneck at present.
However, to ensure for any rhino species to survive, it’s necessary not only to protect them in wild areas where they live, but also to reduce demand for rhino horn, especially in countries of East Asia like Vietnam and China. At the same time, it’s necessary put pressure on the countries with the highest consumption of rhino horns to enforce existing laws and to take effective measures to halt the trade in rhino horns. Another important measure is to reduce corruption in the source countries and transit countries, and in the countries where rhino horns are illegally sold.

















